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Serum Calcium Combined with CRP in Early Prediction of Hemorrhagic Transformation After Stroke Thrombolysis

Combined Detection of Serum Calcium Levels and CRP for Early Prediction of Hemorrhagic Transformation After Thrombolysis in Stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119580
Enrollment
Unknown
Registered
2026-02-28
Start date
2026-02-28
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

The group of patients with stroke thrombolysis without bleeding:None
Patients with hemorrhagic transformation after thrombolysis for stroke:None
The group of patients with stroke who did not receive thrombolysis treatment:None

Sponsors

The First Affiliated Hosipital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Met the diagnostic criteria for ischemic stroke and were confirmed by MRI examination; no thrombolytic treatment was administered; 2. Met the diagnostic criteria for ischemic stroke and were confirmed by MRI examination; all received thrombolytic treatment, and the time from onset to thrombolysis was less than 4.5 hours. No hemorrhagic transformation was observed in the head MRI examination of the patients; 3. Patients who experienced hemorrhagic transformation on MRI examination 24 hours after thrombolytic treatment.

Exclusion criteria

Exclusion criteria: 1. The MRI examination indicated the presence of intracranial hemorrhage; 2. Comorbid with other cardiovascular and cerebrovascular diseases; 3. Had a history of brain injury or intracranial hemorrhage in the past; 4. Was accompanied by cancer, severe infectious diseases, hematological disorders, etc.

Design outcomes

Primary

MeasureTime frame
The level of CRP in the serum;Serum calcium level combined with CRP test results;

Countries

China

Contacts

Public ContactDeng Li

The First Affiliated Hosipital of Kunming Medical University

280218318@qq.com+86 871 6532 4888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026