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Study on Time-Domain Interference Stimulation to Improve Upper Limb Function After Stroke

Analysis of the Efficacy and Safety of Time-Domain Interference Stimulation in Treating Upper Limb Dysfunction After Stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119573
Enrollment
Unknown
Registered
2026-02-28
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Group B:TI sham stimulation Conventional rehabilitation therapy
Group A:Time-domain Interference Stimulation (TI) Conventional Rehabilitation Therapy

Sponsors

Yuebei People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosed with ischemic or hemorrhagic stroke by CT or MRI; 2.First-time unilateral lesion accompanied by unilateral upper limb dysfunction, in the subacute stage of stroke, with disease course between 2 weeks and 6 months; 3.Age between 18 and 80 years; 4.Mini-Mental State Examination (MMSE) score >= 24, without severe cognitive or communication impairments; 5.Apart from routine medications for underlying conditions, no other drugs have been used;

Exclusion criteria

Exclusion criteria: 1.Patients with severe systemic diseases such as cardiovascular or pulmonary conditions that cannot tolerate rehabilitation therapy; 2.Patients diagnosed with severe depression or other mental disorders; 3.Patients with other neurological diseases such as Parkinson's disease or epilepsy, in addition to stroke; 4.Presence of metallic foreign bodies in the skull or other electronically implanted devices; 5.Currently using medications that alter cortical excitability; 6.Patients diagnosed with tumors;

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Upper Extremity Section;

Secondary

MeasureTime frame
Brunnstrom staging;Modified Ashworth scale score;Wolf motor function test result;ADL index;

Countries

China

Contacts

Public ContactXiao Bao

Yuebei People’s Hospital

baoxiao1981@Sina.com+86 751 6913256

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026