sepsis
Conditions
Interventions
exposed group:none
non-exposed group:none
Sponsors
Fifth Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients admitted to the Fifth Affiliated Hospital of Sun Yat-sen University between January 1, 2022, and December 31, 2025; 2.Age >= 18 years; 3.Confirmed diagnosis of sepsis; 4.Presence of diagnostic criteria for MASLD (exposed group) or explicit exclusion of MASLD (unexposed group); 5.Informed consent for whole blood sample collection has been obtained;
Exclusion criteria
Exclusion criteria: 1.Concurrent chronic liver diseases: such as hepatitis B/C, autoimmune liver disease, alcoholic hepatitis, cirrhosis, etc. 2.Excessive alcohol consumption (daily ethanol intake exceeding 20 grams for women or 30 grams for men); 3.Pregnancy; 4.Significant data missing: such as lack of diagnostic criteria for MASLD or 28-day outcome information;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In hospital mortality;28-day all-cause mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of ARDS;Incidence of Acute Kidney Injury;Incidence of Renal Replacement Therapy;Infection Control Duration;Hospitalization expenses;Duration of invasive mechanical ventilation;Duration of Hospitalization;Incidence of MODS;Incidence of septic shock;Incidence of invasive mechanical ventilation; | — |
Countries
China
Contacts
Public ContactYao Lan
Fifth Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed