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Clinical and Mechanistic Study on Lactobacillus curvatus Improving Endometritis and Enhancing IVF Clinical Pregnancy Rates

Clinical and Mechanistic Study on Lactobacillus curvatus Improving Endometritis and Enhancing IVF Clinical Pregnancy Rates

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119551
Enrollment
Unknown
Registered
2026-02-28
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometritis with infertility

Interventions

A:Antibiotic and placebo intervention
B:Antibiotic + Lactobacillus curvatus intervention

Sponsors

The Ninth Hospital of Nanchang
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Between the ages of 20 and 40, married, with regular sexual life, and without contraception for more than 1 year without successful pregnancy; 2. not having chronic abdominal pain or lumbosacral pain; 3. Have not used vaginal medication or probiotic preparations; 4. His male partner does not have oligo, weak, abnormal or azoospermia that causes female infertility.

Exclusion criteria

Exclusion criteria: 1. Other uterine pathologies: uterine malformations such as uterine adhesions, submucosal fibroids, and longitudinal uterine septum; 2. combination of endometriosis, ovarian tumours, tubal effusion; 3. patients with female hormonal abnormalities and unexplained bleeding; 4. or patients with uterine and/or adnexal pressure and pain in gynaecological examination and suspected pelvic inflammatory disease; 5. patients with serious cardiovascular, cerebrovascular, hepatic and renal dysfunction diseases that are not suitable for IVF/ICSI treatment or pregnancy.

Design outcomes

Primary

MeasureTime frame
Intrauterine Microecological Indicator Testing;Clinical pregnancy rate;Pregnancy Outcome Monitoring Following IVF/ICSI;

Secondary

MeasureTime frame
Baseline indicators;

Countries

China

Contacts

Public ContactXia He

The Ninth Hospital of Nanchang

hx794622@163.com+86 791 8849 9520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026