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The efficacy of 2 cycles versus 3 cycles of induction chemotherapy in patients with locally advanced nasopharyngeal carcinoma

The efficacy of 2 cycles versus 3 cycles of induction chemotherapy in patients with locally advanced nasopharyngeal carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119540
Enrollment
Unknown
Registered
2026-02-28
Start date
2026-03-15
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

local advanced nasopharyngeal carcinoma

Interventions

2-cycle IC group:None
3-cycle IC group:None

Sponsors

The First Affiliated Hospital of Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.be aged between 18 and 70 years; 2.be histologically confirmed to be stage III-IVA (based on the 8th edition of the AJCC/UICC staging system); 3.received two or three cycles of IC combined with CCRT; 4.had Eastern Cooperative Oncology Group performance status of 0 or 1; 5.had no severe hematological, liver and kidney toxicity; 6.had complete clinical, examination, and follow-up data.

Exclusion criteria

Exclusion criteria: 1.had metastatic NPC at initial diagnosis or progression after systemic therapy; 2.had prior history of other malignant tumors; 3.be failured to receive and complete IC combined with CCRT.

Design outcomes

Primary

MeasureTime frame
local recurrence-free survival (LRFS);progression-free survival (PFS);distant metastasis-free survival (DMFS);overall survival (OS);—

Countries

China

Contacts

Public ContactWu Sangang

The First Affiliated Hospital of Xiamen University

uno12345@163.com+86 592 213 9531

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026