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A prospective study on the effects of different jet ventilation modes under rigid bronchoscopy on the collapse index of the inferior vena cava (CTI)

A prospective study on the effects of different jet ventilation modes under rigid bronchoscopy on the collapse index of the inferior vena cava (CTI)

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119517
Enrollment
Unknown
Registered
2026-02-28
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who need EBUS treatment under rigid bronchoscopy due to lung diseases

Interventions

SHFJV group:The ventilation mode is set to superimposed high-frequency jet ventilation mode.
HFJV group:The ventilation mode is set to high frequency jet ventilation mode.
NFJV group:The ventilation mode is set to normal frequency jet ventilation mode.

Sponsors

Emergency General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-75 years old; 2.ASA classification I-III; 3.It is planned to perform a rigid bronchoscopy (including tumor resection, foreign body removal, and stenosis shaping, etc.) and to use jet ventilation. 4.The estimated duration of the surgery is 30 to 60 minutes. 5.Preoperative ultrasound can clearly measure the inferior vena cava (IVC) with a diameter of 1.0 - 2.5 cm and a respiratory variation of >=10%.

Exclusion criteria

Exclusion criteria: 1.Severe right heart failure, pulmonary hypertension or severe tricuspid regurgitation (affecting the interpretation of IVC diameter); 2.Previous inferior vena cava surgery / filter or obvious inferior vena cava anatomical abnormality; 3.Pregnancy or severe electrolyte imbalance (serum potassium 5.5 mmol/L); 4.Patients who cannot undergo IVC ultrasound (due to body type, incision, wound, etc.); 5.Those who have undergone emergency intubation and cannot complete steady-state measurements. 6.Expected severe airway obstruction and need for special ventilation strategies. 7.More than 10 ml/kg of fluid resuscitation within 6 hours before the operation.

Design outcomes

Primary

MeasureTime frame
haemodynamics;

Secondary

MeasureTime frame
Arterial blood gas indicators;baseline information;Security Index;

Countries

China

Contacts

Public ContactYuxue Yao

Emergency General Hospital

729163581@qq.com+86 10 8793 5413

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026