Cerebral small-vessel disease, CSVD
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patient age >= 18 years; 2.Acute ischemic stroke patients admitted within 7 days of onset and diagnosed according to the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2023. 3.Patients with complete brain MRI and blood laboratory data.
Exclusion criteria
Exclusion criteria: 1.Severe mental illness; 2.Patients with severe hepatic or renal impairment, infection, or malignancy. 3.Incomplete clinical data;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between C-FAR levels at admission and total CVSD burden score in patients with acute ischemic stroke.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between C-FAR and individual CSVD imaging markers (lacunar infarcts, WMH, CMBs, PVS);The optimal cutoff value of C-FAR for predicting moderate to severe CSVD (total burden score >2); | — |
Countries
China
Contacts
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology