Psoriasis combined with high risk of diabetes
Conditions
Interventions
Treatment group:Conventional treatment+TGP(24 wks)
control group:Conventional treatment(24 wks)
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine. Affiliated toShanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meets the Western medicine diagnostic criteria for mild to moderate psoriasis vulgaris; 2. Identified as having a high risk of diabetes mellitus comorbidity based on predictive model calculations; 3. Aged >=18 years and <=75 years, regardless of gender; 4. Agrees to participate in this study and signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed with diabetes or insulin resistance; 2. Patients diagnosed with spleen deficiency syndrome according to Traditional Chinese Medicine (TCM); 3. Patients with other active skin diseases that may affect disease assessment; 4. Patients who have received systemic treatment with investigational drugs, biological agents, or immunosuppressants within the past month; 5. Patients who have received topical corticosteroids, phototherapy, etc., within the past two weeks; 6. Patients experiencing severe, uncontrollable local or systemic acute or chronic infections; 7. Patients with severe systemic diseases; or patients whose clinical test indicators fall into one of the following categories: ALT or AST elevated > 1.5 times the upper limit of normal; creatinine elevated > 1.5 times the upper limit of normal; blood... Patients whose routine key indicators (white blood cell count, red blood cell count, hemoglobin level, platelet count) are below the lower limit of normal; or whose other laboratory tests are abnormal and the researcher deems them unsuitable for participation in this trial; 8. Patients with a history of malignant tumors, primary or secondary immunodeficiency, or hypersensitivity; 9. Patients who have undergone major surgery within the past 8 weeks or will undergo such surgery during the study period; 10. Pregnant or lactating women; 11. Patients with a history of alcoholism, drug abuse, or substance abuse; 12. Patients with a history or family history of severe mental illness; 13. Patients with a family history of cancer; 14. Patients deemed unsuitable for participation in this study for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diabetes/Insulin Resistance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Psoriasis Area and Severity Index, PASI;Body Surface Area, BSA;Physician Global Assessment, PGA;Dermatology Life Quality Index, DLQI;Patient-Reported Quality of Life, PRQoL;VAS;blood lipid tests;Inflammatory factors; | — |
Countries
China
Contacts
Public ContactXin Li
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed