Kawasaki disease, uveitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Fever, and at least 4 out of the following 5 main clinical features are present, namely: non-exudative conjunctival congestion in both eyes; changes in the lips and oral cavity, such as dry redness, fissuring, congestion of the lips, strawberry tongue, and diffuse congestion of the oral and pharyngeal mucosa; acute non-suppurative lymph node enlargement in the neck (usually with a diameter > 1.5 cm); polymorphic rashes, including redness and swelling around keloids; changes at the extremities, such as redness of the palms and soles during the acute phase, hard edema of the hands and feet during the recovery phase, and membranous desquamation around the nails of the fingers and toes, with or without coronary artery lesions. 2.Fever persists for 5 days or more, or if the fever duration is irregular, and there are 2 or 3 of the 5 main clinical features present, and there is a clear echocardiographic change indicating coronary artery dilation, namely: the Z value of the left or right coronary artery is >=2.0; or the coronary artery characteristics meet the criteria for coronary artery dilation (inner diameter 4 mm for those 5 years old or older, and/or the adjacent inner diameter is expanded by>= 1.5 times or the lumen is significantly irregular). 3.Age >= 3 years old;
Exclusion criteria
Exclusion criteria: 1.Children who are unable to cooperate with the examination;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of KD-associated uveitis; Presence of coronary artery dilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome and duration of KD-related uveitis;Whether IVIG intolerance; | — |
Countries
China
Contacts
Children's Hospital of Chongqing Medical University