Prevention and management strategies for postoperative nausea and vomiting in patients undergoing craniotomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600119507

Enrollment

Unknown

Registered

2026-02-28

Start date

2026-03-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing craniotomy

Interventions

Control group:Standard perioperative management protocol for neurosurgery

Experimental group:A multi-disciplinary collaborative and multi-modal comprehensive PONV intervention strategy

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. This is the first time for a craniotomy surgery; 3. Clear consciousness, informed consent, and voluntary participation in this study.

Exclusion criteria

Exclusion criteria: 1. Severe heart, lung, liver and kidney dysfunction; 2. Previous chronic digestive system diseases; 3. Patients experiencing nausea and vomiting due to pregnancy, chemotherapy or radiotherapy; 4. Insensitive or allergic to the fragrant smells of mint, lemon, lavender, etc.; 5. Patients with mental disorders, cognitive impairments or hearing impairments who are unable to communicate or cooperate.

Design outcomes

Primary

Measure	Time frame
The incidence of PONV within 24 hours postoperatively;The time to the first onset of PONV;The severity of PONV;The situation of rescue antiemetic drugs used within 24 hours after the surgery due to PONV;	—

Secondary

Measure	Time frame
Postoperative recovery of gastrointestinal function;Quality of Recovery-15 Scale Score;	—

Countries

China

Contacts

Public ContactWenyao Cui

West China Hospital, Sichuan University

cuiwenyao07@126.com+86 189 8060 6082

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026