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Comparative Observation of the Analgesic Efficacy of Anrikefon and Fentanyl in Painless Induced Abortion Surgery: A Prospective, Single-Center, Blinded, Randomized Controlled Trial

Comparative Observation of the Analgesic Efficacy of Anrikefon and Fentanyl in Painless Induced Abortion Surgery: A Prospective, Single-Center, Blinded, Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119493
Enrollment
Unknown
Registered
2026-02-27
Start date
2026-03-02
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless abortion surgery pain

Interventions

Anrikefon(A) Group:Group A received an intravenous bolus of Anruikefen at the 95% effective dose ( calculated based on body weight), followed by an intravenous bolus of propofol at 2 mg/kg.
Fentanyl (F) Group:Group F received an intravenous bolus of fentanyl at 1.5 µg/kg, followed by an intravenous bolus of propofol at 2 mg/kg.

Sponsors

The First People's Hospital of Yunnan Province
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1.Aged 20-40 years, with an American Society of Anesthesiologists (ASA) physical status classification of I-II; 2.Patients scheduled for painless induced abortion surgery; 3.Body Mass Index (BMI) 18-28 kg/m^²; 4.Gestational age <= 10 weeks; 5.Has provided written informed consent;

Exclusion criteria

Exclusion criteria: 1.Patients with known allergies to opioids, propofol, or anrikefon; 2.Chronic use of sedative or analgesic medications; 3.Severe cardiac, pulmonary, hepatic, or renal dysfunction; 4.Difficult airway, or fasting time < 6 hours; 5.Presence of conditions predisposing to postoperative nausea and vomiting (eg:vertigo); 6.Presence of psychiatric disorders or cognitive impairment that may impede cooperation with study assessments.

Design outcomes

Primary

MeasureTime frame
VAS Pain Score;

Secondary

MeasureTime frame
Analgesic Rescue Medication Use;Perioperative Vital Signs;Use of Rescue Sedatives;recovery time;PACU length of stay;Incidence and Severity of Postoperative Nausea and Vomiting (PONV);Incidence and Severity of Postoperative Pruritus;Incidence and Severity of Postoperative Dizziness and Drowsiness;Satisfaction assessment;

Countries

China

Contacts

Public ContactLuo Jing

The First People's Hospital of Yunnan Province

2292940670@qq.com+86 180 8798 8614

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026