Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for the Case Group (1)Children are aged 6-17 years. Adults are older than 18 years; (2).Meeting the clinical diagnostic criteria for osteoarthritis (OA) as outlined in the Chinese Guidelines for the Diagnosis and Treatment of Osteoarthritis (2024 Edition); (3).Planned to undergo minimally invasive or open surgery, with no long-term prior administration of lipid-regulating medications such as statins before the operation; (4).Voluntarily participating in this study and signing the informed consent form. 2.Inclusion Criteria for the Control Group (1)Children are aged 6-17 years. Adults are older than 18 years; (2).No history of arthritis, and scheduled for minimally invasive surgery due to knee joint injuries such as meniscal lesions, ligament tears and other related conditions; (3).voluntarily participating in this study and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Exclusion Criteria (1).Patients with comorbidities of other malignant tumors or severe hepatic and renal insufficiency; (2).Patients who have received intra-articular corticosteroid injections, long-term treatment with non-steroidal anti-inflammatory drugs, or treatment with lipid-regulating medications within the past 3 months; (3).Female patients who are in the pregnancy, lactation, or menstrual period; (4).Patients who refuse to provide complete clinical data or cooperate with sample collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatty acid;Blood Test Report; | — |
Secondary
| Measure | Time frame |
|---|---|
| General demographic information;Physical examination;Medical history;Treatment history;Family history;Dietary Habits; | — |
Countries
China
Contacts
School of Public Health, Sun Yat-sen University (Shenzhen)