Skip to content

Study on the Pathogenesis of Knee Osteoarthritis Based on Abnormal Lipid Metabolism

Study on the Pathogenesis of Knee Osteoarthritis Based on Abnormal Lipid Metabolism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119484
Enrollment
Unknown
Registered
2026-02-27
Start date
2026-02-27
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Interventions

Sponsors

School of Public Health, Sun Yat-sen University (Shenzhen)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Inclusion Criteria for the Case Group (1)Children are aged 6-17 years. Adults are older than 18 years; (2).Meeting the clinical diagnostic criteria for osteoarthritis (OA) as outlined in the Chinese Guidelines for the Diagnosis and Treatment of Osteoarthritis (2024 Edition); (3).Planned to undergo minimally invasive or open surgery, with no long-term prior administration of lipid-regulating medications such as statins before the operation; (4).Voluntarily participating in this study and signing the informed consent form. 2.Inclusion Criteria for the Control Group (1)Children are aged 6-17 years. Adults are older than 18 years; (2).No history of arthritis, and scheduled for minimally invasive surgery due to knee joint injuries such as meniscal lesions, ligament tears and other related conditions; (3).voluntarily participating in this study and signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Exclusion Criteria (1).Patients with comorbidities of other malignant tumors or severe hepatic and renal insufficiency; (2).Patients who have received intra-articular corticosteroid injections, long-term treatment with non-steroidal anti-inflammatory drugs, or treatment with lipid-regulating medications within the past 3 months; (3).Female patients who are in the pregnancy, lactation, or menstrual period; (4).Patients who refuse to provide complete clinical data or cooperate with sample collection.

Design outcomes

Primary

MeasureTime frame
Fatty acid;Blood Test Report;

Secondary

MeasureTime frame
General demographic information;Physical examination;Medical history;Treatment history;Family history;Dietary Habits;

Countries

China

Contacts

Public ContactZhen Wang

School of Public Health, Sun Yat-sen University (Shenzhen)

wangzh663@mail.sysu.edu.cn+86 136 5165 1078

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026