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A Study on the Transgenerational Impact of Dynamic Glucose Variation Trajectories Based on Continuous Glucose Monitoring on Maternal and Infant Ocular Health During Pregnancy

A Study on the Transgenerational Impact of Dynamic Glucose Variation Trajectories Based on Continuous Glucose Monitoring on Maternal and Infant Ocular Health During Pregnancy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119464
Enrollment
Unknown
Registered
2026-02-27
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational glucose abnormalities

Interventions

Distinct maternal gestational blood glucose trajectory groups:None

Sponsors

Chongqing Health Center for Women and Children (Women and Children's Hospital of Chongqing Medical University)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Enrolled and registered at our hospital in early pregnancy (gestational age <13 weeks), and plans to complete subsequent prenatal check-ups and delivery at our hospital; 2.Aged 18 years or above; 3.Singleton pregnancy; 4.Voluntarily participates in this study, signs the informed consent form, and commits to being able and willing to complete the following requirements according to the study protocol: (1) Undergoes standardized oral glucose tolerance test screening during pregnancy; (2) Wears and uses continuous glucose monitoring devices and wearable devices (such as Xiaomi Band 10) as required; (3) Completes research questionnaires regularly; (4) Provides biological samples as required; 5.Has a fixed residence locally, no plans to relocate during the study period, ensuring the ability to complete study follow-up; 6.No severe underlying diseases (such as heart, liver, kidney dysfunction, etc.); 7.No diseases that may affect blood glucose or exercise capacity, such as no motor dysfunction, no history of severe exercise-impairing injuries in the past 6 months; 8.No history of ocular diseases before pregnancy (such as retinopathy, ocular trauma, etc.).

Exclusion criteria

Exclusion criteria: 1.Serious Pregnancy Complications: Have or develop serious pregnancy complications at enrollment or during the study, such as preeclampsia, placental abruption, uncontrolled thyroid disease, etc.; 2.Contraindications to CGM or Wearable Devices (e.g., severe allergy or discomfort); 3.Inability to Proficiently Use Smartphones or Related Monitoring Devices After Training; 4.Other Exclusionary Conditions: The investigator determines the existence of any other condition that makes the participant unsuitable for this study (e.g., psychiatric illness preventing cooperation, history of substance abuse, etc.).

Design outcomes

Primary

MeasureTime frame
Gestational blood glucose;Vision;Intraocular pressure;Fundus imaging;Macular thickness;Corneal nerve density;Diopter;Axial length;Corneal curvature;Retinal vascular morphology;

Countries

China

Contacts

Public ContactMeng Xiao

Chongqing Health Center for Women and Children (Women and Children's Hospital of Chongqing Medical University)

984530150@qq.com+86 150 8696 1072

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026