Lung nodules require localization of the patient
Conditions
Interventions
The conventional treatment group:Before patient positioning, a conventional local anesthesia method was used, where 2% lidocaine was applied for surface anesthesia.
Oral administration group:Sixty minutes before the patient positioning, the intervention of oral pregabalin capsules (75mg) + tramadol/acetaminophen tablets (37.5mg/325mg) was carried out.
Intravenous administration group:Before patient positioning, an intravenous injection of flurbiprofen axetil solution (50mg) was administered as an intervention 15 minutes prior.
Sponsors
The Affiliated Drum Tower Hospital of Nanjing University Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age >= 18 years old, with good cognitive and comprehension abilities; (2) American Society of Anesthesiologists (ASA) classification of grades I to III; (3) Signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Have severe neurological or mental disorders and epilepsy; (2) Be allergic to pregabalin and tramadol, acetaminophen, or flurbiprofen; (3) Have taken 5-hydroxytryptamine drugs (such as selective 5-hydroxytryptamine reuptake inhibitors and monoamine oxidase inhibitors) recently; (4) Regularly take other analgesics (such as opioid drugs); (5) Have a history of chronic chest pain; (6) Body Mass Index (BMI) >= 30 kg/m^2; (7) Unable to communicate normally, such as hearing impairment and language comprehension impairment; (8) Had severe cardiovascular or cerebrovascular diseases or liver and kidney dysfunction before the surgery; (9) Have severe respiratory diseases or obvious respiratory depression; (10) Have a history of lung surgery; (11) Other conditions that make one unsuitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery rate of analgesia; | — |
Countries
China
Contacts
Public ContactZhao Gefei
The Affiliated Drum Tower Hospital of Nanjing University Medical School
Outcome results
None listed