Preoperative Anxiety
Conditions
Interventions
Dexmedetomidine nasal spray group:Preoperatively, dexmedetomidine is sprayed intravenously into the nose
Dexmedetomidine intravenous infusion group:Preoperative intravenous infusion of dexmedetomidine
Saline group:Saline nasal spray
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age 18~70 years old. 2. ASA grade I-II. 3. BMI18.5~28Kg/m^2. 4. Elective painless gastroenteroscopy is planned. 5. The heart, kidney, liver and other organs function normally, and there are no cognitive, audio-visual and sensory disorders. 6. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe cardiopulmonary disease (eg, uncontrolled hypertension, bradycardia <50 beats/min, atrioventricular block). 2. History of nasal deformity, allergic rhinitis, or recent nasal surgery. 3. Chronic use of sedative/anxiolytic medications or alpha-2 agonists. 4. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety level; | — |
Secondary
| Measure | Time frame |
|---|---|
| depth of sedation;hemodynamic stability;anesthetic dosage;quality of postoperative recovery;satisfaction; | — |
Countries
China
Contacts
Public ContactHua Wei
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed