Effects of Early Physical Therapy in Critically Ill Patients: Prospective Observational Study Based on Quadriceps Muscle Ultrasound Measurements

Evaluation of the Effect of Early Physical Therapy in Critically Ill Patients: A Prospective Study Based on Ultrasound Measurement of the quadriceps femoris

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600119453

Enrollment

Unknown

Registered

2026-02-27

Start date

2026-03-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical illness

Interventions

Observation group (divided into exposure group and control group according to the presence or absence of physical therapy):None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. predicted duration of mechanical ventilation >=7 d; 2.age >=18 years and <=80 years; 3.no brain organic lesions; 4.voluntary participants after communication with the patient's family.

Exclusion criteria

Exclusion criteria: 1.primary motor dysfunction or definite neuromuscular disease; 2.lumbar spine, pelvis, lower extremity trauma or surgery; 3.limb defects; 4.maternal; 5.redness, swelling, bleeding and other conditions at the measurement points of both lower limbs; (6) anticipated death or palliative care.

Design outcomes

Primary

Measure	Time frame
Rectus femoris cross-sectional area, rectus femoris thickness, and vastus intermedius thickness;Medical Research Council (MRC) muscle strength score;Duration of mechanical ventilation;	—

Secondary

Measure	Time frame
ICU length of stay;	—

Countries

China

Contacts

Public ContactZhou Zhaobin

The First Affiliated Hospital,Jiangxi Medical College, Nanchang University

915775696@qq.com+86 183 7096 0205

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026