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Effect of Intraoperative FiO2 Regulation Combined with Lung Recruitment Maneuver on Alveolar Maintenance Efficacy in Patients Undergoing Head and Neck Surgery

Effect of Intraoperative FiO2 Regulation Combined with Lung Recruitment Maneuver on Alveolar Maintenance Efficacy in Patients Undergoing Head and Neck Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119409
Enrollment
Unknown
Registered
2026-02-26
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atelectasis

Interventions

Group A:After anesthetic induction and full onset of drug effects, endotracheal intubation was performed with the fraction of inspired oxygen (FiO2) set at 40%. Following the initiation of surgery, Fi
Group B :After anesthetic induction and full onset of drug effects, endotracheal intubation was performed with the fraction of inspired oxygen (FiO2) set at 40%. Lung recruitment maneuver was conducte
Group C :After anesthetic induction and full onset of drug effects, endotracheal intubation was performed with the fraction of inspired oxygen (FiO2) set at 40%. Following the initiation of surgery, F
Group D :After anesthetic induction and full onset of drug effects, endotracheal intubation was performed with the fraction of inspired oxygen (FiO2) set at 40%. Following the initiation of surgery, F

Sponsors

Subei People's Hospital of Jiangsu
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with ASA Physical Status Classification ?-?; 2. Voluntarily participate in this study and sign the informed consent form; 3. Patients undergoing elective head and neck surgery under general anesthesia; 4. No restriction on gender; aged 18-64 years; Body Mass Index (BMI) 18-25 kg/m²; 5. Patients with an expected operation duration of >=1.5 hours and estimated intraoperative blood loss of <=200 ml.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of thoracic surgery; 2. Patients with chest X-ray or CT indicating pneumothorax or pulmonary bullae; 3. Patients with pulmonary diseases, including chronic bronchitis, asthma, and moderate to severe obstructive ventilatory dysfunction; 4. Patients with preoperative pulse oxygen saturation (SpO2) < 90% while breathing ambient air, or SpO2 < 95% with oxygen supplementation; 5. Patients with contraindications for lung recruitment, including high intracranial pressure, hypovolemic shock, and right heart failure; 6. Patients with severe heart diseases, including New York Heart Association (NYHA) Class ? or ? heart failure, acute coronary syndrome, and sustained ventricular tachyarrhythmia; 7. Patients currently participating in other interventional studies, or those who refuse to be enrolled.

Design outcomes

Primary

MeasureTime frame
Lung compliance response time;

Secondary

MeasureTime frame
Hypoxemia;Oxygenation index;Atelectasis;Pulmonary complications;

Countries

China

Contacts

Public ContactJu Gao

Subei People's Hospital of Jiangsu province

doctor2227@163.com+86 180 5106 3988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026