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A longitudinal study on the association of reproductive tract and intestinal microecology with recurrence of cervical lesions in high-risk HPV-positive patients

A longitudinal study on the association of reproductive tract and intestinal microecology with recurrence of cervical lesions in high-risk HPV-positive patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119392
Enrollment
Unknown
Registered
2026-02-26
Start date
2026-03-02
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Risk HPV-positive female

Interventions

Case series:none

Sponsors

Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18-65 years; 2. Non-pregnancy and non-feeding women with a sexual history; 3. HR-HPV-infected patients who have not undergone cervical surgery, physical, photodynamic or drug-based treatment; 4. Voluntary participation in this study and signing a informed consent form.

Exclusion criteria

Exclusion criteria: 1. History of use of antibiotics and antifungal drugs for the past 3 months; 2. History of sexual life, vaginal irrigation, and local drug use for the past 1 week; 3. History of absence of constipation, diarrhea, and other discomfort symptoms for the past 1 month; 4. History of acute genital tract inflammation unsuitable for vaginal sampling; 5. History of total hysterectomy and pelvic radiotherapy; 6. History of combined immune system disease, diabetes, and severe liver and kidney dysfunction; 7. History of malignancy or tuberculosis or organ transplantation; 8. History of confirmed HIV infection.

Design outcomes

Primary

MeasureTime frame
Microecological characteristics of reproductive tract;

Countries

China

Contacts

Public ContactWei Wang

Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine

gyfyywangwei@126.com+86 20 83062650

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026