limbs Fractures
Conditions
Interventions
Experimental Group:Bupivacaine liposome was used for local infiltration anesthesia during the operation
Control group:Ropivacaine was used for local infiltration anesthesia during the operation
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 Age of 18-80 years old, limb fractures undergoing open reduction and internal fixation (=2 weeks after injury); 2 Complete clinical data; 3ASA grade I-III; 4 sign the informed consent, follow the doctor's advice, and cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: 1 History of allergy or contraindication to local anesthetics; 2 History of chronic pain > 3 months or long-term use of opioids; 3 hepatic and renal insufficiency; 4 pathological fracture or open fracture; 5 patients did not cooperate with follow-up after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;Range of motion of the affected limb; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total opioid consumption in 72 hours;Functional SCORE; | — |
Countries
China
Contacts
Public ContactCheng Long
West China Hospital, Sichuan University
Outcome results
None listed