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Clinical Phenotypes and Fluctuation Trajectories of Delirium in Critically Ill Patients: A Retrospective Cohort Study

Exploring a Dynamic Trajectory Prediction Model for ICU Delirium Based on Clinical Phenotypic Characteristics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119369
Enrollment
Unknown
Registered
2026-02-26
Start date
2026-03-03
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICU delirium

Interventions

Observation group:None

Sponsors

Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. ICU length of stay > 24 hours.

Exclusion criteria

Exclusion criteria: 1. Pre-existing severe cognitive impairment prior to admission (e.g., severe dementia); 2. Severe primary neurological disorders (e.g., severe traumatic brain injury, massive cerebral infarction, or intracerebral hemorrhage); 3. Persistent coma throughout the ICU stay (Richmond Agitation–Sedation Scale [RASS] consistently -4 or -5), precluding delirium assessment; 4. Absence of delirium assessment records during the ICU stay; 5. Missing data rate >20% for key variables (e.g., APACHE II score, daily SOFA score, and daily RASS and CAM-ICU assessments).

Design outcomes

Primary

MeasureTime frame
Incidence of delirium;Duration of delirium;—

Secondary

MeasureTime frame
ICU length of stay;28-day mortality;Mechanical ventilation duration;—

Countries

China

Contacts

Public ContactLuxi Deng

Xiangya Hospital of Central South University

lucydeng89@163.com+86 158 0268 1098

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026