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Clinical study of inspiratory muscle strength training on respiratory function and quality of life in patients with mechanical ventilation after weaning

Clinical study of inspiratory muscle strength training on respiratory function and quality of life in patients with mechanical ventilation after weaning

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119360
Enrollment
Unknown
Registered
2026-02-26
Start date
2025-11-05
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with mechanical ventilation

Interventions

Inspiratory muscle training group:Conventional rehabilitation therapy+inspiratory muscle strength training
Control group:Conventional rehabilitation therapy

Sponsors

The Second Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-80 years, any gender; 2. Received mechanical ventilation with intubation for =4 days, and have successfully been weaned off the ventilator for >=48 hours; 3. Vital signs and hemodynamics are stable; 4. Conscious, alert, able to cooperate with staff, with a Riker Sedation-Agitation Scale score of 4; 5. Cognitive function is relatively intact, with an MMSE score >=17; 6. Able to follow clinical treatment plans and sign the participant informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with unstable vital signs and hemodynamics, or those considered suitable for palliative care; 2. Severe respiratory diseases, or pregnancy; 3. Severe cognitive or communication impairments, inability to cooperate with staff for training due to consciousness status, Riker Sedation-Agitation Scale 4; 4. Experiencing severe pain affecting respiratory function (e.g., rib fractures); 5. Patients intubated due to neuromuscular diseases; 6. Subjects participating in other clinical trials at the same time; 7. Subjects deemed unsuitable for this trial by the investigator or who voluntarily withdraw.

Design outcomes

Primary

MeasureTime frame
Maximal inspiratory pressure;Range of motion of the diaphragm;Diaphragm thickness;

Secondary

MeasureTime frame
SF-36 quality of life scale score;Borg dyspnea score;

Countries

China

Contacts

Public ContactYu Lehua

The Second Affiliated Hospital of Chongqing Medical University

300895@cqmu.edu.cn+86 138 9617 9179

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026