Postoperative pain after thoracoscopic surgery
Conditions
Interventions
Vagus Nerve Block (VNB):Localization:
Right vagal nerve block: At the level of the lower trachea, infiltration injection was performed under direct thoracoscopic visualization in the space between the
bilateral vagal nerve block was strictly prohibited.
Sham Group:The identical puncture and operation procedure as that in the VNB group were performed. After the needle tip reached the target position, only 3 ml of 0.9% normal saline was injected.
Sponsors
The 8th Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age>= 18 years; 2.Elective video-assisted thoracic surgery (VATS) for pulmonary wedge resection/segmentectomy/single lobectomy; 3.American Society of Anesthesiologists (ASA) physical status classification I–III; 4.Signed informed consent form
Exclusion criteria
Exclusion criteria: 1.Anticipated difficult airway; 2.Severe respiratory diseases (such as asthma, chronic obstructive pulmonary disease, bronchiectasis, etc.) or severe impairment of pulmonary function (forced expiratory volume in the 1st second [% of predicted], FEV1% 1.4 or platelet count 30 mg oral morphine equivalent, OME per day) or gabapentin/pregabalin; 6.Known allergy to local anesthetics used in the protocol; 7.Pregnant or lactating women; 8.Presence of cognitive or psychiatric disorders that prevent completion of patient-reported outcome assessments; 9.Severe heart diseases (New York Heart Association, NYHA III-IV, severe arrhythmias) and severe hepatic or renal insufficiency; 10.Other conditions deemed unsuitable for participation in this study by the researchers.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 scale 48 hours after surgery;Length of stay in PACU;Length of postoperative hospital stay;Incidence of emergence agitation;Patient satisfaction score;Postoperative pain NRS score;Opioid consumption at 48 hours postoperatively;Use of non-opioid analgesics;Number of rescue analgesic administrations;Incidence of PONV;Time to first flatus / defecation;Levels of inflammatory factors;Incidence of chronic pain at 3 months; | — |
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 scale 24 hours after surgery; | — |
Countries
China
Contacts
Public ContactAn Ni
The 8th Center of Chinese PLA General Hospital
Outcome results
None listed