oral lichen planus
Conditions
Interventions
Control group:Apply triamcinolone acetonide Oral ointment locally to the affected area
Experimental group:Photodynamic local irradiation on the affected area of oral mucosa combined with local application of triamcinolone acetonide oral ointment on the affected area
Sponsors
The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Be capable of giving informed consent and signing the informed consent form;2. Age over 18 years old (including the critical value); 3. Erosive OLP that was diagnosed clinically and histopathologically and met the diagnostic criteria of WHO 2003; 4. Erosion/ulcerative damage occurs on the oral mucosa and the affected area is >=5mm ^2.
Exclusion criteria
Exclusion criteria: 1. Suffering from uncontrolled hypertension, heart disease, diabetes or other systemic diseases; 2. Accompanied by other oral mucosal diseases; 3. Received immunotherapy within 3 months or received local or systemic treatment of OLP within 1 week; 4. Those who have been clearly diagnosed with drug-induced lichenoid damage; 5. Patients suspected of having contact lichenoid lesions; 6. Patients with oral lichenoid damage related to tumors, including those with oral lichenoid damage induced by radiotherapy, chemotherapy, etc; 7. Pregnant or lactating patients; 8. People allergic to triamcinolone acetonide and methylene blue.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficiency rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Apparent efficiency rate;Recovery rate;Visual analogue scale scale;Oral Health Impact Profile scale;The degree of impact on oral health;Subjective discomfort level; | — |
Countries
China
Contacts
Public ContactJunjun Chen
The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed