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A study on the pathways of Cognitive dysfunction and its influencing Factors in late-life depression Based on the Structural Equation Model

A study on the pathways of Cognitive dysfunction and its influencing Factors in late-life depression Based on the Structural Equation Model

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119318
Enrollment
Unknown
Registered
2026-02-25
Start date
2024-05-13
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Late life depression

Interventions

Observation Group of Depression in the Elderly:None

Sponsors

Suzhou Guangji Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. After being diagnosed by a professional physician, it meets the criteria for severe depression as stipulated in the Fourth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). 2. Age >= 60 years old, with no obvious visual or auditory impairments. 3. Clear consciousness and clear language expression. 4. Voluntary participation with informed consent and signing of the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those diagnosed with diseases such as Parkinson's disease, stroke, cerebral hemorrhage, dementia, etc., and whose condition is unstable. 2. Those who have comorbid other severe mental disorders, mental retardation, mental disorders caused by the abuse of psychoactive substances that affect brain function or cognitive function assessment, or other physical diseases, and are not suitable to participate in this study as determined by professional physicians.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment Scale score;

Secondary

MeasureTime frame
Connection test;Elderly Depression Scale Score;Daily Living Ability Scale Score;Pittsburgh Sleep Quality Index Score;Magnetic Resonance Imaging;

Countries

China

Contacts

Public ContactXia Zhao

Suzhou Guangji Hospital

17858368692@163.com+86 512 6579 7433

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026