After hip and knee replacement surgery
Conditions
Interventions
the frail group and the non-frail group:None
Sponsors
Wuxi Mental Health Center/ Wuxi Central Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. First-time unilateral total hip or total knee replacement surgery; 2. No severe dysfunction in the contralateral limb (muscle strength >= grade 4); 3. Clear consciousness and informed consent.
Exclusion criteria
Exclusion criteria: 1. A clear diagnosis of frailty before surgery (Fried phenotype >= 3 items); 2. Complicated with malignant tumors or autoimmune diseases; 3. Long-term use of glucocorticoids or immunosuppressants; 4. Inflammatory arthropathy or neuromuscular disease; 5. A history of major surgery or severe infection within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nutritional indicators;Bilateral muscle structure and function;gut microbiota;ROC curve; | — |
Countries
China
Contacts
Public ContactXie Dan
Wuxi Mental Health Center/ Wuxi Central Rehabilitation Hospital
Outcome results
None listed