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Effects of rTMS combined with upper limb multichannel FES on early brain activation and brain functional network after stroke

Effects of rTMS combined with upper limb multichannel FES on early brain activation and brain functional network after stroke

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119294
Enrollment
Unknown
Registered
2026-02-25
Start date
2024-12-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Control group:Conventional rehabilitation therapy
FES group:Perform functional electrical stimulation therapy
rTMS group:Perform repetitive transcranial stimulation therapy
Joint group:Functional electrical stimulation and repetitive transcranial magnetic stimulation therapy were carried out

Sponsors

Beijing Rehabilitation Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for stroke; 2. Head CT or MRI shows a unilateral lesion, and the onset was within 3 months; 3. General condition and vital signs are stable, with no obvious cognitive impairment. The Mini-Mental State Examination (MMSE) score is greater than 24, and the patient can cooperate with the assessment and treatment; 4. Age is between 30 and 70 years old, and the Brunnstrom stage of the affected upper limb is II to IV; 5. The patient voluntarily participates in this study and signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Progressive or secondary stroke; 2. Modified Ashworth scale for muscle tone of the affected upper limb or hand >= 2; 3. Patients with peripheral nerve injury or history of peripheral neuropathy in the upper limb; 4. Individuals or those with a family history of epilepsy, severe heart, lung, liver, kidney and other organ diseases; 5. Patients with pacemakers, cochlear implants and other metal implants.

Design outcomes

Primary

MeasureTime frame
Functional near-infrared spectroscopy,fNIRS;Fugl-Meyer assessment of the upper extremity,FMA-UE;

Countries

China

Contacts

Public ContactLv Xueying

Beijing Rehabilitation Hospital Affiliated to Capital Medical University

2269074921@qq.com+86 10 5698 1051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026