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Determination of the Minimum Effective Concentration of Ropivacaine for Ultrasound-Guided Erector Spinae Plane Block in Postoperative Analgesia after Thoracoscopic Surgery

Determination of the Minimum Effective Concentration of Ropivacaine for Ultrasound-Guided Erector Spinae Plane Block in Postoperative Analgesia after Thoracoscopic Surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119286
Enrollment
Unknown
Registered
2026-02-25
Start date
2025-03-31
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain in patients undergoing thoracoscopic surgery

Interventions

Test group:T5-ESPB was performed under ultrasound guidance, and 24 ml of ropivacaine was administered at different concentrations.

Sponsors

The First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Plan to undergo thoracoscopic lobectomy in our hospital; 2. Aged 18 to 75 years old, height 150-180cm, and BMI 18 to 35 kg/m^2; 3. American Society of Anesthesiologists (ASA) grade I to III; 4. Gender is not limited.

Exclusion criteria

Exclusion criteria: 1. The patient refuses and is unable to give informed consent; 2. Unable to cooperate in completing the research plan; 3. Pregnant, parturient, or with a positive urine pregnancy test; 4. Preoperative use of analgesic drugs or drugs that affect neurological function; 5. Opiate addiction and dependence; 6. Those with contraindications to ESPB such as spinal deformity, coagulation abnormalities, puncture site infection, or mental illness, etc. who are unable to cooperate; 7. Those who are allergic to local anesthetics or intraoperative drugs; 8. Unable to understand or use visual analogue scale (VAS) pain scoring and patient controlled intravenous analgesia (PCIA).

Design outcomes

Primary

MeasureTime frame
numerical rating scale,NRS;

Secondary

MeasureTime frame
Number of PCA presses and total postoperative rescue opioid analgesic consumption at 12h, 24h, and 48h postoperatively;Incidence, severity, and correlation of adverse events (AEs) and serious adverse events (SAEs) with the study drug;

Countries

China

Contacts

Public ContactChunmei Wang

The First Affiliated Hospital of Dalian Medical University

wangchunmei@firsthosp-dmu.com+86 13079881000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026