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Clinical study on the effect of Oliceridine on postoperative gastrointestinal dysfunction in patients undergoing spinal surgery.

Clinical study on the effect of Oliceridine on postoperative gastrointestinal dysfunction in patients undergoing spinal surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119280
Enrollment
Unknown
Registered
2026-02-25
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative gastrointestinal dysfunction

Interventions

sufentanil group:Intraoperative and postoperative analgesia was provided with sufentanil
Oliceridine group:Oliceridine was used instead of sufentanil for intraoperative and postoperative analgesia

Sponsors

Shaanxi Nuclear Industry 215 Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Elective spinal surgery; 2. Age 18-70 years; 3. Body mass index (BMI) 18-30 kg/m²; 4. American Society of Anesthesiologists (ASA) physical status classification ?-?.

Exclusion criteria

Exclusion criteria: 1. History of long-term opioid use; 2. Preoperative history of gastrointestinal disease, constipation, or abdominal surgery; 3. Concomitant severe heart, lung, or renal dysfunction; 4. Refusal to use a postoperative patient-controlled analgesia (PCA) pump; 5. Postoperative hemodynamic instability or respiratory insufficiency; 6. Other conditions deemed by the investigator to make continuation of the study impossible or inappropriate.

Design outcomes

Primary

MeasureTime frame
postoperative gastrointestinal dysfunction;

Secondary

MeasureTime frame
Whether gastrointestinal decompression, enema and consultation are caused by POGD;Length of hospital stay and hospitalization expenses;Effectiveness of postoperative pain control;The occurrence of adverse reactions related to postoperative analgesic pumps;

Countries

China

Contacts

Public ContactJia Liu

Shaanxi Nuclear Industry 215 Hospital

2651676969@qq.com+86 29 32088351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026