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ffectiveness of Multimodal Nutritional Management in Patients With Severe Traumatic Brain Injury: A Randomized Controlled Trial

Construction of multimodal nutritional management programs for patients with severe craniocerebral injury and evaluation of clinical effects

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119253
Enrollment
Unknown
Registered
2026-02-25
Start date
2025-12-16
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic Brain Injury

Interventions

Intervention group:multi-modal nutrition management program
Control group:Standard nutritional support

Sponsors

The First Affiliated Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years, meeting the diagnostic criteria for severe craniocerebral trauma as outlined in the "Guidelines for the Management of Severe Traumatic Brain Injury"; 2. No contraindications to enteral nutrition; 3. Receiving continuous nutritional therapy for >=5 days after admission to the ICU; 4. Giving informed consent to participate in this study and signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with major underlying diseases (such as end-stage tumors) or gastrointestinal diseases that prevent the implementation of enteral nutrition; 2. Patients with an expected survival time of less than 72 hours; 3. Patients who are transferred to another hospital or withdraw from the treatment pathway during the treatment process.

Design outcomes

Primary

MeasureTime frame
infection incidence rate;

Secondary

MeasureTime frame
Recovery degree of neurological function;Improvement indicators of nutritional status;The incidence of gastrointestinal complications;Hospitalization process indicators;

Countries

China

Contacts

Public ContactYe Zhixue

The First Affiliated Hospital of Ningbo University

fyyezhixue@nbu.edu.cn+86 138 5789 1235

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026