Postoperative Cognitive Dysfunction
Conditions
Interventions
Single general anesthesia group:None
Sponsors
Anhui Provincial Public Health Clinical Center (The North District of the First Affiliated Hospital of Anhui Medical University)
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Wound surgery patients scheduled for superficial surgical procedures at our hospital, with ASA physical status classification I-III; (2) Aged 40–80 years, regardless of gender; (3) Normal communication ability and capable of cooperating with cognitive function assessments; (4) Informed consent obtained.
Exclusion criteria
Exclusion criteria: (1) Patients with severe organic diseases or autoimmune diseases; (2) Patients with psychiatric disorders, impaired consciousness, or cognitive/language dysfunction; (3) Patients with severe preoperative infection or sepsis; (4) Patients with abnormal neurological sensation in the affected limb; (5) History of any cerebrovascular accident within the past 3 months, such as stroke or transient ischemic attack; (6) History of anesthesia drug allergy or relevant anesthesia contraindications; participation in other drug clinical trials within the past 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative Delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative Cognitive Dysfunction;Incidence of Anxiety and Depression;Sleep Quality Score; | — |
Countries
China
Contacts
Public ContactHuang Tingting
Anhui Provincial Public Health Clinical Center (The North District of the First Affiliated Hospital of Anhui Medical University)
Outcome results
None listed