Pancreatic tumors
Conditions
Interventions
Gold Standard:The histopathological results of surgically resected specimens or needle biopsy are used as the final diagnosis
Index test:Virtual Enhanced CT Generation System Based on Conditional Diffusion Models
Sponsors
Shanghai Changhai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Pancreatic tumour group: pathologically confirmed pancreatic tumour (PDAC or other tumour); 3. normal control group: initial imaging reported as normal pancreas and no progression of pancreatic lesions on >=6 months imaging follow-up (CT or MRI) during the retrospective collection 2015-2025; 4. have complete plain, arterial phase and portal phase enhanced CT data from the same examination; 5. Layer thickness of =5mm and complete coverage of the pancreas and surrounding key vessels; 6. For the subset of resectability assessment: detailed surgical records and postoperative pathology reports must be available.
Exclusion criteria
Exclusion criteria: 1. Those who have a history of pancreatic treatment or major upper abdominal surgery that has significantly changed their anatomical structure; 2. Severe metal artifacts or motion artifacts in the image, resulting in unreadable anatomy; 3. The real enhancement CT reinforcement effect is not good and cannot be used as the training truth value; 4. The registration of the flat scan and enhanced images fails, and paired training data cannot be constructed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Area under the ROC curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Structural similarity;Peak signal-to-noise ratio; | — |
Countries
China
Contacts
Public ContactKai Cao
Shanghai Changhai Hospital
Outcome results
None listed