Somatosensation, Pain and Analgesia
Conditions
Interventions
Opioid free group (OFA group):No opioids were used intraoperatively.
Low opioid group (LOA group):Limited opioids were allowed based on the same baseline protocol.
Sponsors
Dazu District People's Hospital of Chongqing
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients aged 18-75 years, 2. ASA physical status I-II, 3. Scheduled for elective laparoscopic cholecystectomy were enrolled, 4. All subjects should be able to understand and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to study drugs or local anesthetics, 2. Severe liver and kidney dysfunction or cardiac insufficiency, 3. History of long-term opioid use or drug dependence, 4. Mental illness, 5. Obesity (BMI >35), 6. Pregnancy or lactation, TAP block failure, etc. 6.Failure of TAP block
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative resting pain at 0–24 hours;OOpioid-related adverse events (0–24 h post-op); | — |
Secondary
| Measure | Time frame |
|---|---|
| Dynamic pain 0–24 h postoperatively;Total opioid use, 24/48 h post-op;Incidence of isolated PONV (:PONV postoperative nausea a;Length of stay in PACU;Time to achieve discharge criteria;Satisfaction of patients and surgeons;QoR-15 score;7-day readmission rate; | — |
Countries
China
Contacts
Public ContactZhou Dan
Dazu District People's Hospital of Chongqing
Outcome results
None listed