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Efficacy and safety of Tegileridine in intravenous analgesia for oral tumors: a multicenter, randomized, double-blind, positive-controlled clinical study.

Efficacy and safety of Tegileridine in intravenous analgesia for oral tumors: a multicenter, randomized, double-blind, positive-controlled clinical study.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119219
Enrollment
Unknown
Registered
2026-02-24
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain in patients undergoing oral tumor surgery

Interventions

Morphine hydrochloride Group:Postoperative continuous intravenous analgesia with Morphine hydrochloride
Tegileridine Group:Postoperative continuous intravenous analgesia with Tegileridine

Sponsors

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged >= 18 and == 60 mL/min); 4. Sign the informed consent form and voluntarily participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients who have been administered opioids or other analgesic medications before surgery; 2. Patients requiring mechanical ventilation or ICU monitoring after surgery; 3. Patients who having severe cardiovascular or respiratory diseases, or a history of drug abuse; 4. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
The resting summed pain intensity difference over 24 hours (rSPID24).;

Secondary

MeasureTime frame
Various vital signs (blood pressure, heart rate, respiratory rate, pulse oximetry, body temperature);SAEs;Quality of life and satisfaction;

Countries

China

Contacts

Public ContactLi Jingjie

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine

116212@sh9hospital.org+86 21 5331 6021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026