Dry eye
Conditions
Interventions
Mild Dry Eye Subgroup (Stage 1):None
Moderate Dry Eye Subgroup (Stage 1):None
Severe Dry Eye Subgroup (Stage 1):None
Healthy Control Subgroup (Stage 1):None
Mild Dry Eye Subgroup (Stage 2):None
Moderate Dry Eye Subgroup (Stage 2):None
Severe Dry Eye Subgroup (Stage 2):None
Healthy Control Subgroup (Stage 2):None
Mild Dry Eye Subgroup (Stage 3):None
Moderate Dry Eye Subgroup (Stage 3):None
Severe Dry Eye Subgroup (Stage 3):None
Healthy Control Subgroup (Stage 3):None
Sponsors
Eye & ENT Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the dry eye group: 1. Age 18–75 years old; 2. Diagnosed with dry eye according to the "Chinese Expert Consensus on Dry Eye (2024)"; 3. Voluntary participation in the study and signing of the informed consent form. Inclusion criteria for the control group: 1. Age 18–75 years old; 2. No history of dry eye or any related subjective symptoms (such as dryness, foreign body sensation, burning sensation, etc.); 3. TBUT > 10 seconds, and corneal fluorescein staining is negative; 4. Voluntary participation in the study and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Having a history of eye allergy or infection within the past 1 month; 2. Allergic to fluorescein sodium; 3. Excessive eyelid relaxation, incomplete eyelid closure, ectropion / entropion, palpebral fissure spots, pterygium or corneal conjunctival scars, and other diseases that affect blinking / closing of the eyes; 4. IOP of any eye > 21 mmHg in the current examination, or a history of glaucoma / high intraocular pressure in the past, or currently receiving anti-glaucoma medication; 5. Severe / serious eye diseases that the researcher judges may interfere with the assessment or compliance; 6. Severe / serious systemic diseases or uncontrolled medical conditions (such as uncontrolled diabetes) that the researcher judges may interfere with the assessment or compliance; 7. Unable / unwilling to cooperate with the research process, such as eye examination, questionnaire filling, or image collection, or having cognitive / comprehension deficiencies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area Under the ROC Curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Accuracy; | — |
Countries
China
Contacts
Public ContactHong Jiaxu
Eye & ENT Hospital of Fudan University
Outcome results
None listed