Hormone receptor-positive HER-2 negative advanced breast cancer
Conditions
Interventions
Palbociclib:None
Abemaciclib:None
Dalpiciclib:None
Ribociclib:None
Sponsors
Weihai Municipal Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Over 18 years old; 2.ECOG<=2 points; 3.The functions of the important organs of the body are normal; 4. New-onset advanced or recurrent metastatic breast cancer that has been clearly identified as HR+/HER2- through relevant examinations; 5.Have at least one measurable lesion; 6. At least 2 cycles of CDK4/6 inhibitor treatment were applied, and at least one efficacy evaluation was received; 7.It has relatively complete clinical data: age, initial diagnosis stage, menstrual status, metastasis site, treatment plan, etc. 8.Complete follow-up data.
Exclusion criteria
Exclusion criteria: 1.Concurrent with other malignant tumors; 2.Loss to follow-up or incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-Free Survival (PFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free Rate at 6 Months;Progression-Free Rate at 12 Months;Objective Response Rate (ORR);Clinical Benefit Rate (CBR); | — |
Countries
China
Contacts
Public ContactYan Xiujuan
Weihai Municipal Hospital
Outcome results
None listed