Unstable Angina
Conditions
Interventions
Experimental group:Based on the standardized drug treatment recommended in the guideline (such as dual antiplatelet therapy, statins, beta-blockers, ACEI/ARB, etc.), 2 puffs (approximately 0.6 mL) of
Control group:The standardized drug treatment regimen was the same as that of the control group. 30 minutes before the PCI procedure, a placebo aerosol (0.9% sodium chloride solution + nitrogen) was a
Sponsors
The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 40 - 75 years old, gender not restricted; 2. Coronary angiography confirmed that at least one major coronary artery was stenosed to = 70%, and planned to undergo elective PCI within 24 - 48 hours; 3. Received >= 24 hours of standardized anti-angina therapy, with stable hemodynamics; 4. Signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Acute ST-segment elevation myocardial infarction or requiring emergency PCI; 2. Severe heart failure (NYHA IV grade or LVEF < 40%), cardiogenic shock, malignant arrhythmia; 3. Severe liver and kidney dysfunction, coagulation disorder, high bleeding risk; 4. Allergic to any component of KXA; 5. Within one week before enrollment, had taken other traditional Chinese medicine for promoting blood circulation and resolving stasis or participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of perioperative myocardial infarction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Markers of myocardial injury;Myocardial perfusion;Incidence of no reflow/slow blood flow during surgery;Symptoms of angina pectoris;Cardiac function;TCM syndrome points; | — |
Countries
China
Contacts
Public ContactXiqi Liu
The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine
Outcome results
None listed