Breast cancer
Conditions
Interventions
Observation group (breast cancer patients):None
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Female patients diagnosed with breast cancer via histopathological examination; 2.Aged between 18 and 70 years; 3.Scheduled to receive standard neoadjuvant therapy (chemotherapy, targeted therapy, or combination immunotherapy); 4.Understand the study content and voluntarily sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Use of systemic antibiotics or oral probiotic/prebiotic preparations within 4 weeks prior to enrollment; 2.History of severe active intestinal diseases (e.g., inflammatory bowel disease, chronic diarrhea, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathological Complete Response, pCR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective response rate on imaging;Treatment-related adverse events;Progression-free survival; | — |
Countries
China
Contacts
Public ContactXingyu Zhou
Peking University Shenzhen Hospital
Outcome results
None listed