None
Conditions
Interventions
EP Group:Epidural Analgesia
DPE Group:Dural Puncture Epidural
DDPE Group:Double Dural Puncture Epidural
Sponsors
First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Primigravida, singleton, cephalic presentation, full-term (=37 weeks), planning for vaginal delivery; 2.Age >= 18 years; 3.Cervical dilation 5; 5.ASA physical status classification II; 6.Voluntarily signs the informed consent form; 7.Feasibility of epidural labor analgesia confirmed after joint assessment by the obstetrician, anesthesiologist, and midwife;
Exclusion criteria
Exclusion criteria: 1.Contraindications to neuraxial anesthesia (e.g., coagulation abnormalities, infection at the puncture site, spinal deformity); 2.Allergy to local anesthetics (ropivacaine or lidocaine) and/or opioids; 3.High-risk pregnancy including placenta previa, preeclampsia, etc. 4.Presence of fetal distress or known fetal abnormalities; 5.History of chronic pain, or concurrent use of analgesics, sedatives, or antidepressants; 6.Language or cognitive barriers that prevent understanding or cooperation with study assessments;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analgesic efficacy at 20 minutes after the initial loading dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of bilateral lower limb motor block;Time to analgesic onset;Durations of the first and second stages of labor;S2 block attainment and time to S2 block;Maternal satisfaction;Highest sensory block level within 20 min of initial loading dose;Mode of delivery;Time to T10 sensory block;Incidence of adverse events from anesthesia initiation to 24 hours postpartum;Number of parturients requiring rescue analgesia and number of PCEA administrations delivered;VAS pain scores;Neonatal Apgar score; | — |
Countries
China
Contacts
Public ContactHaiyu Xie
First Affiliated Hospital of Gannan Medical University
Outcome results
None listed