Cardiac arrest
Conditions
Interventions
Trial group:Adopt an individualized blood pressure management approach guided by cerebral autoregulation.
Control group:Adopt the traditional target blood pressure management approach: maintain the mean arterial pressure at least at 65 mmHg.
Sponsors
The Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years old; 2. Those undergoing VA-ECMO treatment; 3. The estimated length of stay in the ICU is no less than 72 hours. 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Conditions interfering with NIRS: frontal lobe surgery, frontal contusion, bilateral forehead hematoma, decompressive craniectomy, subdural/epidural hematoma, effusion, pneumocephalus, intracerebral hemorrhage, intracranial tumor, intracranial infection, cerebral infarction. 2.Pregnancy or advanced malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GOSE scores;The modified Rankin score.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Local cerebral oxygen saturation (in this study, rcSO2 was recorded using NIRS);Cerebral oxygenation index;Peak systolic velocity of the middle cerebral artery;End diastolic velocity of the middle cerebral artery;Mean velocity of the middle cerebral artery;Resistance index of the middle cerebral artery;Pulsatility index of the middle cerebral artery;The ICU mortality rate;The ICU stay time;Total hospital stay time;Total hospitalization cost; | — |
Countries
China
Contacts
Public ContactZhou Baochun
The Second Affiliated Hospital of Soochow University
Outcome results
None listed