Chill
Conditions
Interventions
experimental group:Remimazolam for anesthesia induction and maintenance
control group:Propofol anesthesia induction and maintenance
Sponsors
Suzhou Hospital Affiliated to Nanjing Medical School (Suzhou Science and Technology City Hospital)
Eligibility
Sex/Gender
Male
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 80 male patients undergoing lower urinary tract surgery, including prostatectomy and transurethral lithotripsy; 2. aged >=65 years; 3. ASA (American Society of Anesthesiologists) class I-III.
Exclusion criteria
Exclusion criteria: 1. Allergy to the investigational drug. 2. Preoperative fever due to infection or other causes. 3. Patients with severe cardiovascular or cerebrovascular diseases, COPD, or coagulation disorders. 4. Intraoperative blood loss>800 mL or operative duration>120 minutes. 5. Presence of skull base fractures or anatomical abnormalities precluding nasopharyngeal esophageal temperature measurement. 6. Severe cognitive impairment precluding follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body temperature; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure (MAP);Heart rate; | — |
Countries
China
Contacts
Public ContactLi Chenguang
Suzhou Hospital Affiliated to Nanjing Medical School (Suzhou Science and Technology City Hospital)
Outcome results
None listed