Post-Stroke Depression
Conditions
Interventions
Brain-Computer Interface Treatment Group:The ankle BCI rehabilitation robot training regimen consists of one 30-minute session per day, administered five days per week, for a total duration of two wee
Music Intervention Combined with BCI Treatment Group:Selective and passive music intervention was implemented, involving communication with patients and their families to identify preferred music genr
Sponsors
Beijing Tsinghua Changgung Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meets the clinical criteria for stroke diagnosis, with the first onset; 2. Meets the ICD-10 criteria for depressive episode, with 8 = 12 points and MoCA < 26 points); no visual field defect or abnormal eye movement; 4. Right-handed; 5. Disease duration < 12 months; 6. Age 18 - 75 years; 7. Certified by the Kinesthetic and Visual Imagery Questionnaire (KVIQ) that the patient can independently perform motor imagery tasks; 8. Stroke patients have unilateral limb movement disorders, with the lower limb of the affected side having Brunnstrom <= 4 grade, ankle dorsiflexion and plantar flexion muscle strength 0 - 4 grades, and lower limb Modified Ashworth grade 0 - II grade; 9. The study was approved by the ethics committee of our hospital, and the patients voluntarily underwent treatment and all signed the informed consent form for treatment.
Exclusion criteria
Exclusion criteria: 1. Patients with severe depression (HAMD-24 >= 35) or suicidal tendencies; 2. Those who are unable to complete the study due to severe aphasia or cognitive impairment; 3. Those with a history of mental or psychological disorders and a history of drug or alcohol abuse; 4. Those who were still taking any antidepressants or drugs that might interfere with cognitive function within 2 weeks before enrollment; 5. Patients whose condition is still unstable, such as a systolic blood pressure > 180 mmHg or diastolic blood pressure > 110 mmHg during rest, heart rate > 120 beats per minute, etc.; 6. Those who are unwilling to participate in this trial for various reasons or have difficulties in completing the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Motor Assessment of Lower Extremity (FMA-LE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale (HAMD-24);Temporal Experience of Pleasure Scale(TEPS);Montreal Cognitive Assessment (MoCA);Modified Barthel Index (MBI);Quantitative Electroencephalography (qEEG) ;Event-Related Potential (ERP);Eye movement characteristic; | — |
Countries
China
Contacts
Public ContactXiaoxue Zhai
Beijing Tsinghua Changgung Hospital
Outcome results
None listed