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Validation of a Screening Model for Asymptomatic Intracranial Arterial Stenosis in Hypertensive Patients

Validation of a Screening Model for Asymptomatic Intracranial Arterial Stenosis in Hypertensive Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119163
Enrollment
Unknown
Registered
2026-02-24
Start date
2025-07-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Hypertension

Interventions

Observational group:None

Sponsors

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients with essential hypertension hospitalized in Ward 2 of the Hypertension Department at Ruijin Hospital between January 1, 2021 and April 30, 2025.

Exclusion criteria

Exclusion criteria: 1.Patients with a history of transient ischemic attack (TIA) or stroke; 2.Patients with prior cardiovascular events, including myocardial infarction, stroke, history of coronary PCI, coronary artery bypass grafting (CABG), or hospitalization for heart failure. 3.Patients who did not undergo cranial MRA during hospitalization.

Design outcomes

Primary

MeasureTime frame
Asymptomatic intracranial arterial stenosis (aICAS);—

Secondary

MeasureTime frame
Model discriminative ability (AUC value);Model sensitivity, specificity, positive and negative predictive values;Model calibration;Model net benefit;Model performance differences across subgroups (stratified analysis by age, sex, hypertension, diabetes, etc.);—

Countries

China

Contacts

Public ContactZhang Jin

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

zj11241@rjh.com.cn+86 21 64370045

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026