Gallbladder Cancer
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Confirmed gallbladder cancer by postoperative pathological examination; 2.Underwent radical resection for gallbladder cancer (R0 or R1 resection), with a surgical extent including at minimum cholecystectomy plus hepatic wedge resection/segment IVb + V resection/right hemihepatectomy combined with regional lymphadenectomy; 3.Complete preoperative baseline clinical data were available, including age, gender, comorbidities, laboratory examinations, and other indicators; 4.Preoperative contrast-enhanced abdominal CT or MRI imaging data of acceptable quality were available (for radiomic analysis); 5.Complete postoperative paraffin-embedded pathological specimens and sections were available (for pathomic analysis and genomic detection); 6.Detailed perioperative data were available for the evaluation of "textbook outcome"; 7.Standardized postoperative follow-up data were available, including definitive records of overall survival and recurrence-free survival.
Exclusion criteria
Exclusion criteria: 1.Patients with synchronous malignant tumors in other organs; 2.Patients with distant metastasis (M1) detected on preoperative imaging or intraoperatively; 3.Patients who received neoadjuvant chemotherapy, radiotherapy or immunotherapy preoperatively (to ensure that preoperative multimodal data can truly reflect the initial status of the tumor); 4.Patients with missing or poor-quality key multimodal data (e.g., imaging, pathological specimens) that render further analysis unfeasible; 5.Patients lost to follow-up or with a follow-up duration of less than 12 months (unless death or tumor recurrence occurred within the 12-month period).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence-free survival;Overall survival; | — |
Countries
China
Contacts
Public ContactZhipeng Liu
The First Affiliated Hospital of Army Medical University
Outcome results
None listed