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The median effective dose of Tegileridine when combined with ciprofol for hysteroscopy

The median effective dose of Tegileridine when combined with ciprofol for hysteroscopy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119132
Enrollment
Unknown
Registered
2026-02-24
Start date
2026-02-05
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscopy

Interventions

Intervention group:Tegileridine was administered intravenously with an initial dose of 15µg/kg and a dose gradient of 1.5µg/kg. The dose was adjusted according to the Dixon modified sequential method.

Sponsors

The People’s Hospital of Suzhou Gaoxin District
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for hysteroscopy; 2. Age 18 to 65 years; 3.Body mass index (BMI) 18 to 28 kg/m^2; 4.American Society of Anesthesiologists (ASA) classification of grade I or II.

Exclusion criteria

Exclusion criteria: 1.One month before the surgery, there was chronic pain or the use of any painkillers; 2.Allergic to opioids; 3.Had a history of mental illness or cognitive dysfunction; 4.Had other somatic pain conditions that might affect the postoperative pain assessment; 5.Unable to complete the pain assessment; 6.Had a history of drug and/or alcohol abuse within 1 year before randomization; 7.Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
ED50 and ED95 of Tigeline;Respiratory rate;End-tidal carbon dioxide;Mean arterial pressure;Heart rate;Pulse oximetry saturation;

Secondary

MeasureTime frame
Pain score;

Countries

China

Contacts

Public ContactSun Yinyin

The People’s Hospital of Suzhou Gaoxin District

869082033@qq.com+86 152 6244 2802

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026