Over active bladder
Conditions
Interventions
Solifenacin:Solifenacin
Solifenacin and kudzu vine root(8g):Solifenacin and kudzu vine root(8g)
Solifenacin and kudzu vine root(4g):Solifenacin and kudzu vine root(4g)
Sponsors
Beijing Bo'ai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age range from 18 to 75 years old, regardless of gender; 2.Voluntary signing of informed consent form; 3.OAB patients who exhibit symptoms such as frequent urination, urgency, nocturia, or urgent urinary incontinence without obvious causes; 4.Urinary frequency, urgency, and nocturia caused by neurological diseases; 5.The urination diary shows patients with an average of >= 8 urinations per 24 hours;
Exclusion criteria
Exclusion criteria: 1. Autonomous urination patients with difficulty urinating; 2.(2) Patients who require indwelling catheterization to empty the bladder; 3.(3) Individuals who are allergic to the research drug or have an allergic constitution; 4.(4) Pregnant, breastfeeding, renal dysfunction (>1.5 times normal), liver function>2 times normal (5) patients with an average 24-hour urine output>200 ml per session or an average 24-hour urination frequency<8 times; 5.(6) Bladder outlet obstruction; 6.(7) Individuals with obvious stress urinary incontinence; 7.(8) Complex or severe urinary tract infections; 8.(9) Individuals who have a preference and a preference for Chinese and Western medicine treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of times the average frequency of urination/catheterization per 24 hours decreased compared to the baseline after 8 weeks of oral treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life Index Score ( QOL);24-hour average urine leakage volume;Wenex Constipation Scoring Sheet;The average number of times of urination/catheterization per 24 hours in the 4th week after administration decreased compared with the baseline;Average volume of urine per urination/catheterization volume;The average number and score of urgent urination within 24 hours;OABSS score;The average number of urinary incontinence cases within 24 hours; | — |
Countries
China
Contacts
Public ContactLu shousi
Beijing Bo'ai Hospital
Outcome results
None listed