None
Conditions
Interventions
Cipropol Group:Cipropol 0.2 mg/kg+SUF(0.1ug/kg)
Propofol Group:Propofol 1 mg/kg+SUF(0.1ug/kg)
Sponsors
Chui Yang Liu Hospital affiliated to Tsinghua University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients aged 65 years or older,female or male, who meet the criteria for pre frailty ; 2.American Society of Anesthesiologists classification(ASA) : I-III; 3.Plan to undergo painless gastroscopy examination at a scheduled time; 4.Signatory of informed consent form;
Exclusion criteria
Exclusion criteria: 1. There are contraindications to conventional endoscopic procedures or refusal of anesthesia; 2.Need for tracheal intubation and clear difficulties in the airway; 3.The patient has the following diseases: circulatory and respiratory diseases that are not properly controlled and may threaten life, severe liver dysfunction (Child Pugh C), severe renal dysfunction, acute upper gastrointestinal bleeding with shock, severe anemia, gastrointestinal obstruction with gastric retention; 4.Without accompanying or guardian; 5.Allergy to any component of the investigational drug, such as opioid drugs, propofol, cipropol and soy; 6.Concomitant severe neurological disorders such as epilepsy; 7.Unable to cooperate with severe mental illness; 8.Have a history of drug abuse; 9.Morbid obesity. 10.Those who do not cooperate or are unable to follow up;. 11.Patients deemed unsuitable by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Induction time;recovery time, and recovery time of orientation,;discharge time,;Drug dosage;the time of inserting gastroscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence rates of each aDuring surgery and before dischargedverse events;Hemodynamic changes at various time points; | — |
Countries
China
Contacts
Public ContactYang Yanwei
Chui Yang Liu Hospital affiliated to Tsinghua University
Outcome results
None listed