Chronic Hepatitis B (CHB)
Conditions
Interventions
Case group:NA
Sponsors
Guangzhou Eighth people's Hospital, Guangzhou Medical University, Guangzhou, China.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Adults aged 18 years or older; 2. Patients with liver nodules detected by imaging, or those diagnosed with liver cirrhosis; 3. Availability of at least one analyzable liver ultrasound image and laboratory test results; 4. Availability of laboratory test results obtained within a close timeframe to the imaging; 5. Complete clinical follow-up data or anticipated follow-up duration of at least 12 months every 6 months.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1. Ultrasound images and laboratory test results not meeting the minimum quality criteria for analysis; 2. Absence of contemporaneous laboratory data or clinical information; 3. Presence of other major comorbidities that may interfere with liver disease assessment; 4. History of liver transplantation or major liver surgery; 5. Unwillingness or inability to comply with follow-up procedures; 6. Patients with decompensated cirrhosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The prediction accuracy for the risk of HCC in patients with cirrhosis within 6 months and 1 year (measured by AUC and time-dependent AUC).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients whose cirrhosis eventually progressed to HCC, including tumor burden at diagnosis (measured by maximum tumor diameter and number of tumors) and treatment modality ; | — |
Countries
China
Contacts
Public ContactJian-Ping Li
Department of Hepatology, Guangzhou Eighth people's Hospital, Guangzhou Medical University, Guangzhou, China.
Outcome results
None listed