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The impact of antiplatelet drugs on short-term bleeding risk after colorectal polypectomy at different recovery times (day after surgery vs. elective surgery): A prospective, multicenter, randomized controlled study

The impact of antiplatelet drugs on short-term bleeding risk after colorectal polypectomy at different recovery times (day after surgery vs. elective surgery): A prospective, multicenter, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119096
Enrollment
Unknown
Registered
2026-02-14
Start date
2026-02-16
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal polyps

Interventions

experimental group:Antiplatelet therapy resumed the following day.
control group:Antiplatelet therapy will be scheduled for the next day.

Sponsors

The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years, scheduled for elective colorectal polyp resection. 2. Long-term antiplatelet therapy (aspirin or P2Y12 inhibitor monotherapy). 3. Polyps assessed as suitable for complete endoscopic resection. 4. Stable clinical condition, able to tolerate endoscopic procedures. 5. Signed informed consent form, agreeing to participate in this study and accept follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients who have recently undergone coronary stent implantation (within 6 months) and require mandatory maintenance of dual antiplatelet therapy. 2. Patients taking oral anticoagulants (warfarin or DOACs) and are unable to discontinue or adjust their medication. 3. High-risk procedures requiring polyp diameter >20 mm or requiring piecemeal resection/ESD. 4. Patients with severe liver or kidney dysfunction, coagulation disorders, or active bleeding. 5. Pregnant or lactating women. 6. Patients unable to complete follow-up or with poor adherence.

Design outcomes

Primary

MeasureTime frame
Impact of postoperative bleeding risk;

Secondary

MeasureTime frame
All-cause mortality rate;Readmission rate, readmission rate (endoscopy/intervention/surgery);Cardiovascular and cerebrovascular events 30 days after surgery;

Countries

China

Contacts

Public ContactLu Chao

The FIrst Affiliated Hospital, College of Medicine, Zhejiang University

chaolu0213@zju.edu.cn+86 571 87236861

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026