renal massive lesions
Conditions
Interventions
Cyclopophenol group:General anesthesia was induced with propofol ( 0.4mg / kg ), sufentanil, midazolam and cisatracurium. After successful induction of anesthesia, after the patient 's muscle relaxati
Propofol group:General anesthesia was induced by propofol ( 2mg / kg ), sufentanil, midazolam and cisatracurium. After successful induction of anesthesia, after the patient 's muscle relaxation and un
Sponsors
first affiliated hospital of anhui medical university
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. patients undergoing elective robotic-assisted laparoscopic partial nephrectomy; 2. Age 20-80 years; 3. American Society of Anaesthesiologists ASA Class I-III; 4. No history of long-term use of analgesic, sedative or anxiolytic drugs; 5. Informed consent, voluntary participation in the trial, and signing the informed consent form. 6. All patients who meet the inclusion criteria will be informed in detail of the purpose of the study, the rights and obligations of the patients, and sign the informed consent form according to their wishes.
Exclusion criteria
Exclusion criteria: 1. patient refusal; 2. pregnancy or breastfeeding; 3. allergy to propofol or cypropofol; 4. patients who have undergone kidney transplantation 5. subjects who, in the opinion of the investigator, should not participate in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative AKI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative estimated glomerular filtration rate;serum cystatin c;serum creatinine level;Anesthetic consumption;operation time;duration of anesthesia;Use of vasoactive drugs;Postoperative quality of life score;Perioperative adverse events occurred;hospital stay after operation;systemic immune-inflammation index;lymphocyte to neutrophil ratio;Urine volume during anesthesia; | — |
Countries
China
Contacts
Public ContactXu Guanghong
first affiliated hospital of anhui medical university
Outcome results
None listed