Postoperative delirium
Conditions
Interventions
Fospropofol Disodium Group:Fospropofol Disodium intravenous anesthesia maintenance
Sevoflurane Group:Sevoflurane inhalation anesthesia maintenance
Sponsors
chongqing university cancer hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age 60-80 years old, gender not limited; 2.American Society of Anesthesiologists (ASA): Grade II-III; 3.Body Mass Index (BMI): >=18.5 kg/m^2 and=2h,&<=5h; 5.Voluntarily participated and signed an informed consent form;
Exclusion criteria
Exclusion criteria: 1.Individuals with contraindications to general anesthesia or a history of anesthesia accidents; 2.Patients with combined traumatic brain injury, intracranial hypertension, stroke, unstable angina, and myocardial infarction; 3. Respiratory insufficiency, acute phase of obstructive pulmonary disease, presence of difficult airways, or difficulty in endotracheal intubation (modified Mahalanobis score III-IV); 4.Uncontrolled diabetes or hypertension; 5.History of drug use, alcohol abuse, or drug dependence; 6.Abuse or long-term use of anesthetics, sedatives, and analgesics; 7. Individuals who are known or suspected to be allergic or contraindicated to the various components of the investigational drug or the standardized use of drugs specified in the protocol (such as sufentanil citrate injection, propofol, remifentanil hydrochloride injection, and propofol disodium injection); 8.Individuals with a history of mental illness or preoperative cognitive impairment; 9. Individuals who have participated in any drug clinical trials within the past month prior to screening; 10. The researchers believe that there are any other factors that are not suitable for participants in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative recovery quality;hemodynamics;Complications during the anesthesia recovery period;pain score; | — |
Countries
China
Contacts
Public ContactQianyun Pang
chongqing university cancer hospital
Outcome results
None listed